A healthy 10-year-old, 33kg boy is brought to the operating room for an open reduction and internal fixation of a radial fracture. A single shot supraclavicular block with 0.2% ropivacaine is planned. After the injection, the patient demonstrates new seizure-like activity, and local anesthetic systemic toxicity (LAST) is suspected. Which of the following statements is true regarding local anesthetic toxicity?