From Myron Yaster, MD:  Merry Christmas to all and wishing you all a happy and healthy New Year! The PAAD will go on hiatus until January 4th.

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Last week we lost two giants in the pediatric anesthesia universe, Jack Downes and Warren Zapol. The week in review was dominated by Jack’s death.

In memoriam: John J. (“Jack”) Downes, MD
By Myron Yaster, MD

In memoriam: Warren Zapol, MD
By David Polaner, MD, FAAP

Remembering the classics: Sedation Guidelines Historical Perspectives Part 1 Foundations
By Charles J. Cote, MD

Remembering the classics: Sedation Guidelines Historical Perspectives Part 2
By Charles J. Cote, MD

Charlie Cote, MD reviews how the sedation guidelines were developed and continue to develop in this two-part series.

Fluids and Antimicrobials and Pressors…. Oh My! Updates on the Management of Pediatric Sepsis
By Myron Yaster, MD and Justin L. Lockman, MD, MSEd

Original article
Weiss SL, Peters MJ, Alhazzani W, Agus MSD, et al. Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. Pediatr Crit Care Med. 2020 Feb;21(2):e52-e106. PMID: 32032273

The management of sepsis is reviewed. Which pressor should be used particularly in neonates is discussed in some detail.

An enormous number of reader responses were received following the announcement of Jack Downes’ death. Here are the highlights…

Reader responses: Jack Downes parts one and two
By Myron Yaster, MD