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Crawling through the Weeds: Searching through the haze and smoking out the truth regarding medical marijuana effects.
Rita Agarwal MD, FAAP, FASA and Elliot Krane MD, FAAP

Original article
Moore RA, Fisher E, Finn DP, Finnerup NB, Gilron I, Haroutounian S, Krane E, Rice ASC, Rowbotham M, Wallace M, Eccleston C. Cannabinoids, cannabis, and cannabis-based medicines for pain management: an overview of systematic reviews. Pain. 2021 Jul 1;162(Suppl 1):S67-S79. PMID: 32804833

The title says it all.

Perioperative Cardiac Arrest in Children: Should we institute mandatory retirement?
Myron Yaster, MD and Justin L. Lockman, MD, MSEd

Original article
Christensen R, Haydar B, Leis A, Mentz G, Reynolds P. Anesthesiologist-related factors associated with risk-adjusted pediatric anesthesia-related cardiopulmonary arrest: a retrospective two level analysis. Paediatr Anaesth. 2021 Dec;31(12):1282-1289. PMID: 34328691

Case mix rather than the anesthesiologist’s age may be the primary determinant of perioperative cardiac arrest.

IV v PO acetaminophen: A randomized controlled trial
Myron Yaster MD, Rita Agarwal MD, and Lynne G Maxwell MD

Original article
Cathy R Lammers, Amy J Schwinghammer, Brent Hall, Robert Scott Kriss, Debbie A Aizenberg, Jamie L Funamura, Craig W Senders, Vinay Nittur, Richard L Applegate 2nd.  Comparison of Oral Loading Dose to Intravenous Acetaminophen in Children for Analgesia After Tonsillectomy and Adenoidectomy: A Randomized Clinical Trial. Anesth Analg. 2021 Dec 1;133(6):1568-1576. PMID: 34304234

Can an oral loading dose of acetaminophen provide equipotent analgesia at lower cost compared to the equivalent IV dose?

Reader’s Responses Dec 6-10

The perioperative cardiac arrest PAAD drew a lot of reader’s responses.